Exploring the role of the tumour microenvironment: what do other cells do? – Dr Jacqui Shields – MRC Cancer Unit

December 12, 2019 @ 9:30 am – 10:30 am
Clinical School Lecture Theatre 2
Louisa Bellis

Cancers are not just masses of malignant cells. Adjacent “normal” cells, which include fibroblasts, endothelial cells, pericytes and immune cells – known as the stroma – form a microenvironment that co-evolves with cancer from its earliest stages to shape progression. The objective of this lecture is to convey the complexity of a tumour and its surrounding stroma. We will cover the components of the tumour microenvironment, their functional roles within a developing tumour and the implications for therapy