Could we treat mental health disorders by disrupting maladaptive memories? – Dr Amy Milton

November 2, 2021 @ 6:00 pm – 7:30 pm
Wolfson Lecture Theatre
Department of Chemistry
Lensfield Road

Many mental health disorders, including post-traumatic stress disorder (PTSD) and drug addiction, persist due to the formation of maladaptive memories. In PTSD, the emotional memory of trauma leads to symptoms including flashbacks, nightmares, and intense psychological distress; in addiction, cues associated with past drug use can precipitate relapse to drug-seeking even after years of abstinence. Might it be possible to target those maladaptive memories therapeutically, to produce long-term alleviation of symptoms? We’ll consider new treatment approaches under development, that aim to do this by exploiting the process of ‘memory reconsolidation’, and how these approaches – which have had success in animal models – could be translated to the clinic.

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