Calendar

For information about attending a Salisbury Cafe Scientifique event, see the Attending an Event section; there is also more general information in the Frequently Asked Questions section and help on making the most of this calendar in the Calendar Help section. If you fancy a night of science outside but close to Salisbury, there is also this filtered list of nearby events.

Sep
30
Mon
2019
Innovation and the Cambridge Cluster: Past, present and future. – Professor Tim Minshall, Institutue for Manufacturing, University of Cambridge
Sep 30 @ 7:30 pm – 9:00 pm

*Development, characteristics and challenges.*

Cambridge has become synonymous with innovation but is also facing many challenges that are likely to impact its future trajectory. This presentation will be divided into three parts that will then lead to an open discussion. Firstly, the focus will be on the way in which this regional cluster has developed the capabilities to be internationally leading for innovation. Secondly, the characteristics of the present innovation cluster – and the unusual ways it works – will be explored. Finally, some of the challenges that have arisen as a result of success and the issues that need to be addressed will be presented.

“Add to calendar”:https://www.addevent.com/event/?lq3804012

“Find out more about this event”:https://www.csar.org.uk/lectures/lectures-2019-2020/20190930/

“Find out more about CSAR membership”:http://www.csar.org.uk/membership/

Oct
14
Mon
2019
Big Data Psychometrics – Dr. David Stilwell, Cambridge University Judge Business School
Oct 14 @ 7:30 pm – 9:00 pm

*Ethical Dilemmas for the Digital Age*

Many researchers, including myself (e.g. Kosinski, Graepel & Stillwell, 2013), have published papers showing that psychological traits like personality and intelligence can be predicted from the digital footprints people leave behind when they use online services like social media. Should this capability be used in practice, and if so under what conditions? The Facebook Cambridge Analytica scandal clearly demonstrates that the public is uneasy when they feel their data was misused, but on the other hand the public also likes their data to be used to personalise recommendations and services. This talk will introduce the big data psychometrics technology and will pose some questions about how companies should use such technologies in practice.

“Add to calendar”:https://www.addevent.com/event/?he3787864

“Find out more about this event”:https://www.csar.org.uk/lectures/lectures-2019-2020/tbc-14oct2019/

“Find out more about CSAR membership”:http://www.csar.org.uk/membership/

Oct
28
Mon
2019
LARMOR LECTURE – Professor Serena Best – title to be confirmed – Professor Serena Best, Department of Materials Science & Metallurgy
Oct 28 @ 6:00 pm – 7:00 pm

Abstract not available

Artificial Intelligence in Opthalmology – Dr. Pearce Keane, Moorfields Eye Hospital
Oct 28 @ 7:30 pm – 9:00 pm

*The Moorfields-DeepMind Collaboration*

Ophthalmology is among the most technology-driven of the all the medical specialties, with treatments utilizing high-spec medical lasers and advanced microsurgical techniques, and diagnostics involving ultra-high resolution imaging. Ophthalmology is also at the forefront of many trailblazing research areas in healthcare, such as stem cell therapy, gene therapy, and – most recently – artificial intelligence. In July 2016, Moorfields announced a formal collaboration with the world’s leading artificial intelligence company, DeepMind. This collaboration involves the sharing of >1,000,000 anonymised retinal scans with DeepMind to allow for the automated diagnosis of diseases such as age-related macular degeneration (AMD) and diabetic retinopathy (DR). In my presentation, I will describe the motivation – and urgent need – to apply deep learning to ophthalmology, the processes required to establish a research collaboration between the NHS and a company like DeepMind, the initial results of our research, and finally, why I believe that ophthalmology could be the first branch of medicine to be fundamentally reinvented through the application of artificial intelligence.

“Add to calendar”:https://www.addevent.com/event/?AW3787987

“Find out more about this event”:https://www.csar.org.uk/lectures/lectures-2019-2020/tbc-28oct2019/

“Find out more about CSAR membership”:http://www.csar.org.uk/membership/

Nov
11
Mon
2019
The Maths of Whole Universes – Professor John D Barrow, Department of Applied Mathematics and Theoretical Physics
Nov 11 @ 6:00 pm – 7:00 pm

Abstract not available

The Next Generation of Children – Professor Lucy Raymond, Cambridge Institute for Medical Research, University of Cambridge
Nov 11 @ 7:30 pm – 9:00 pm

*How children with rare diseases can be helped by whole genome sequence analysis.*

“Add to calendar”:https://www.addevent.com/event/?af3803299

“Find out more about this event”:https://www.csar.org.uk/lectures/lectures-2019-2020/tbc-11nov2019/

“Find out more about CSAR membership”:http://www.csar.org.uk/membership/

Nov
25
Mon
2019
Dr Susannah Gibson – title to be confirmed – Dr Susannah Gibson, Affiliated Scholar, Department of History and Philosophy of Science
Nov 25 @ 6:00 pm – 7:00 pm

Abstract not available

Jan
17
Fri
2020
Human Origins – Dr Adam Rutherford, Author, Broadcaster
Jan 17 @ 5:30 pm – 6:30 pm

Abstract not available

Jan
24
Fri
2020
Mysteries of Modern Physics – Professor Sean Carroll, Caltech
Jan 24 @ 5:30 pm – 6:30 pm

Abstract not available

Jan
27
Mon
2020
G I TAYLOR LECTURE – Professor Nigel Peake – title to be confirmed – Professor Nigel Peake, Department of Applied Mathematics and Theoretical Physics
Jan 27 @ 6:00 pm – 7:00 pm

Abstract not available

Pioneering genetic therapies for Huntington’s disease and its relevance for neurodegeneration – Professor Sarah Tabrizi, University College London
Jan 27 @ 7:30 pm – 9:00 pm

*An overview of antisense oligonucleotide therapies in development for neurodegenerative diseases.*

There are no effective disease modifying therapies for neurodegenerative diseases such as Alzheimer’s (AD), Parkinson’s (PD), amyotrophic lateral sclerosis (ALS) or Huntington’s disease (HD). Huntington’s disease (HD) is a devastating autosomal dominantly inherited neurodegenerative disease and the genetic predictability of HD provides an opportunity for early therapeutic intervention many years before overt symptom onset and at a time when reversal or prevention of neural dysfunction may still be possible. As HD is monogenetic, fully penetrant, and characterised by a long premanifest phase, it is emerging as a potential model for studying therapeutic intervention in other neurodegenerative conditions such as Alzheimer’s or Parkinson’s disease where no preclinical diagnostic tests exist. In addition, HD manifests with a broad range of clinical symptoms and signs, many of them common to these other diseases, and involves widespread pathology throughout most of the brain involving similar protein misfolding. Understanding of HD pathogenesis is evolving, and I will present an overview of important approaches in development for targeting mutant HTT DNA and RNA, the cause of HD pathogenesis, and in particular I will present our recent successful phase 1b/2a clinical trial testing the effects of antisense oligonucleotide therapy (ASO) with RG6042 (formerly known as IONIS HTT Rx) in patients with early Huntington’s Disease and present the results of the first successful HTT-lowering drug trial (Tabrizi et al New England Journal of Medicine 2019). This study is the first to demonstrate antisense-mediated protein suppression in patients with a neurodegenerative disease. While this particular ASO holds great promise for HD, our findings have broader implications. These data suggest that antisense technology has the potential to provide disease-modifying benefits in other neurodegenerative diseases associated with aberrant production of proteins, including ALS, Alzheimer’s disease and many other diseases that currently lack adequate treatments. In my talk I will review ASO approaches in development for CNS diseases.

“Add to calendar”:https://www.addevent.com/event/?hB3803314

“Find out more about this event”:https://www.csar.org.uk/lectures/lectures-2019-2020/huntingtons/

“Find out more about CSAR membership”:http://www.csar.org.uk/membership/

Jan
31
Fri
2020
Decoding the Heavens: The Antikythera Mechanism – Dr Jo Marchant, Journalist, Author
Jan 31 @ 5:30 pm – 6:30 pm

Abstract not available

Feb
7
Fri
2020
Alan Turing and the Enigma Machine – Dr James Grime, Mathematician, Lecturer
Feb 7 @ 5:30 pm – 6:30 pm

Abstract not available

Feb
14
Fri
2020
The Enigma of Emotion – Dr Tiffany Watt Smith, Queen Mary, University of London
Feb 14 @ 5:30 pm – 6:30 pm

Abstract not available

Feb
21
Fri
2020
The Enigmatic Premodern Book – Dr Erik Kwakkel, University of British Columbia
Feb 21 @ 5:30 pm – 6:30 pm

Abstract not available

Feb
26
Wed
2020
HONORARY FELLOWS LECTURE – Professor David Baulcombe FRS- title to be confirmed – Professor Sir David Baulcombe, Department of Plant Sciences
Feb 26 @ 6:00 pm – 7:00 pm

Abstract not available

Feb
28
Fri
2020
Volcanic Behaviour – Dr Tamsin Mather, University of Oxford
Feb 28 @ 5:30 pm – 6:30 pm

Abstract not available

Mar
6
Fri
2020
Archaeological Mysteries – Dr Albert Yu-Min Lin, Explorer
Mar 6 @ 5:30 pm – 6:30 pm

Abstract not available

Mar
20
Fri
2020
The Futures of Medicine – One Day meeting – Organisers: Professor Ashok Venkitaraman and Dr James Fraser @ Cambridge University Engineering Department LT0
Mar 20 @ 9:00 am – 5:15 pm

Abstract not available